Active Chemical Compounds of TCM Herba Leonuri: Implications for Cardiovascular Disease
Fudan University scientists discover a compound derived from Herba Leonuri, a herb used as a traditional Chinese medicine in collaboration with a world-leader in biopharmaceutical innovation teams to study the mechanism of action of leonurine. Understanding the role of leonurine in Cardiovascular Disease (CVDs )such as chronic heart failure, ischemic stroke, and atherosclerosis may ultimately help in the development of novel medicines.
With over 100 million people with heart disease, China is the ‘diabetes capital of the world.’ CVDs are a major complication of diabetes; about 65 percent of people with diabetes die from heart disease and stroke.
“Understanding the structure and properties of natural substances may open doors to potential drug targets and provide innovative pathways to explore in the fight against major health burdens including CVD,” said Principal Investigator for the research at Fudan University, Professor of Pharmacology and Dean of the School of Pharmacy, Dr Yi-Zhun Zhu.
Indications of Leonurus(Yi Mu Cao):
Menstrual disorders, delayed or absent menses, irregular menses, amenorrhea, dysmenorrha, endometriosis, infertility, PMS, lower abdominal pain, placenta leakage, dystocia, retained placenta, postpartum abdominal pain due to blood obstruction, postpartum pain and bleeding, hematuria, hypertension, nephritis, kidney stones, edema, dysuria, hematuria (blood in urine), lump in the breast, skin infections, skin eruptions.
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